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HeartFlow

Category: AI in Healthcare

A non-invasive, AI-powered precision coronary care platform that helps clinicians diagnose and treat heart disease using data from a standard coronary CT scan. HeartFlow was founded in 2007. The company is led by John Farquhar. Based in Redwood City, California, USA. Team size: 501-1000. Total funding raised: Over $936 million. Latest round: $215 million Series F (April 2023). Key investors include Baillie Gifford, Wellington Management, The Rise Fund (TPG), Fidelity Management & Research, Bain Capital Life Sciences, Janus Henderson Investors.

Founded
2007
Headquarters
Redwood City, California, USA
Team size
501-1000
Total funding
Over $936 million

Value proposition

Enables precise diagnosis and treatment planning for coronary artery disease without invasive procedures, reducing unnecessary diagnostic angiograms, lowering costs, and improving patient outcomes.

Products and solutions

Heartflow FFRct Analysis, Heartflow Plaque Analysis, Heartflow RoadMap Analysis

Unique value

The first and only company to offer a non-invasive, AI-driven FFRct (Fractional Flow Reserve from CT) analysis that provides a functional assessment of coronary artery blockages from a standard CT scan.

Target customer

Hospitals, cardiologists, and radiologists specializing in cardiovascular diagnostics.

Industries served

Healthcare, Medical Diagnostics

Technology advantage

Combines deep learning with computational fluid dynamics to create a personalized 3D model of the heart, reducing the need for invasive procedures by over 83% and providing a clear, data-driven pathway for patient care.

How they differentiate

HeartFlow's primary differentiator is its focus on functional assessment (blood flow) via FFRct, whereas competitors primarily focus on anatomical analysis (plaque characterization and quantification).

Main competitors

Cleerly, Artrya, Philips (through its acquisition of Circle CVI), CathWorks, Vista.ai, inHEART

Key partnerships

Siemens Healthineers, NHS England

Notable customers

NHS England, Cleveland Clinic, Mount Sinai Health System, Munson Medical Center, Charleston Area Medical Center

Major milestones

Received FDA clearance for FFRct Analysis (2014), Obtained national recommendation from NICE in the UK, Secured a national contract with NHS England for widespread adoption, Announced a strategic partnership with Siemens Healthineers, FDA clearance for new products including RoadMap Analysis, Plaque Analysis, and Planner (2022-2023), Closed $215 million in Series F funding (2023)

Growth metrics

Technology has been used to manage over 200,000 patients and is adopted in more than 750 hospitals worldwide.

Market positioning

Market leader in non-invasive FFRct analysis, supported by extensive clinical evidence, strong regulatory approvals (FDA, NICE), and significant commercial adoption.

Geographic focus

Global, with a strong presence in the United States, United Kingdom (via a national contract with NHS), Europe, and Japan.

Patents and IP

Holds a significant portfolio of patents related to its FFRct technology, medical image processing, and computational fluid dynamics for cardiovascular applications.

About John Farquhar

Previously served as Executive Chairman at Cydar Medical and held senior executive roles at Medtronic, including Vice President of the Aortic, Peripheral, & embolization businesses.

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