Isaac Health
Category: AI in Healthcare
An AI-enabled brain health platform that provides a virtual-first clinical model for the screening, diagnosis, and management of dementia and other cognitive disorders. Isaac Health was founded in 2022. The company is led by Julius Bruch. Based in New York, USA. Team size: 101-500. Total funding raised: $16.3M. Latest round: Series A, $10.5M, 2025-08, led by N/A. Key investors include Flare Capital Partners, Meridian Street Capital, B Capital, Primetime Partners, Black Opal Ventures, Industry Ventures.
- Founded
- 2022
- Headquarters
- New York, USA
- Team size
- 101-500
- Total funding
- $16.3M
Value proposition
Reduces specialist wait times from months to days while delivering validated clinical outcomes, including a 38% reduction in Emergency Department utilization and a 28% reduction in hospital stays.
Products and solutions
Virtual Brain Health & Memory Clinic, AI-Powered Early Detection & Screening Tools, Smart Care Management Platform, Specialist-Led Behavioral & Mental Health Services, Dementia-Trained Care Navigator Program, Lifestyle Medicine for Better Brain Health (8-week virtual group program, launched Mar 2026)
Unique value
Combines proprietary AI screening with a behavioral neurology-led specialist model to provide 'Center of Excellence' level care in regions lacking local neurology infrastructure.
Target customer
Medicare Advantage and Medicaid health plans, risk-bearing health systems, Accountable Care Organizations (ACOs), and patients/caregivers in 'neurology deserts.'
Industries served
Healthcare Technology (Healthtech), Artificial Intelligence, Neurology & Geriatrics, Value-Based Care, Elder Care & Caregiver Support
Technology advantage
Leverages predictive machine learning to identify at-risk patients early and integrates directly into value-based care workflows to close Medicare Advantage coding gaps and reduce total cost of care.
How they differentiate
Isaac Health differentiates through a 'virtual-first' clinical model that combines proprietary AI-driven screening tools with specialist-led care, specifically optimized for value-based care (VBC) contracts and the CMS GUIDE model.
Main competitors
Rippl Care, Synapticure, Linus Health
Key partnerships
LillyDirect (Eli Lilly) for expanded dementia care access, Pearl Health for physician enablement in value-based care, CaringKind for community-based caregiver support, CMS GUIDE Model participant, NYU Langone Health for virtual brain health and memory care pathway (Jan 2026), Wellabe for free brain health screening access for insurance customers (Feb 2026), ATRIO Health Plans for Medicare Advantage dementia care (Nov 2025), Major national and regional Medicare Advantage plans
Notable customers
Eli Lilly (LillyDirect), Pearl Health, NYU Langone Health, Wellabe, ATRIO Health Plans, Medicare Advantage Plans, CaringKind
Major milestones
Selected as a participant in the CMS GUIDE (Guiding an Improved Dementia Experience) Model, Partnered with Eli Lilly’s LillyDirect to expand access to specialized dementia care, Named to the 2025 and 2026 New York Digital Health 100, Partnered with NYU Langone Health for expert brain health and memory care (Jan 2026), Partnered with Wellabe for early Alzheimer’s/dementia detection access (Feb 2026), Launched neurology-led virtual Lifestyle Medicine for Better Brain Health program (Mar 2026), Series A $10.5M led by Flare Capital Partners; available in all 50 US states
Growth metrics
38% reduction in ED utilization and 28% reduction in hospital stays for enrolled patients; 73% of patients with improved neurocognitive function over six months; 92% improved against cognitive goals within three weeks (per company Series A disclosures).
Market positioning
Specialized brain health and dementia care provider targeting the Medicare Advantage and Medicaid populations in 'neurology deserts.'
Geographic focus
United States (Nationwide, with a focus on regions lacking local neurology infrastructure)
Patents and IP
Holds patented AI screening capabilities for the detection and assessment of cognitive decline.
About Julius Bruch
Julius Bruch is a physician-scientist and former Associate Partner at McKinsey & Company, where he spent 7 years leading the healthcare practice's work in value-based care and digital health across the US, Europe, and Asia. He holds an MD and a PhD in Clinical Neurosciences from the University of Cambridge, specializing in neurodegenerative diseases.
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Official website: https://isaac.health