Trially AI
Category: AI in Healthcare
An AI-native clinical trial enrollment platform that matches, engages, and enrolls patients with breakthrough speed and accuracy. Trially AI was founded in 2023. The company is led by Kyle McAllister. Based in Kansas City, Missouri, United States. Team size: 1-10. Total funding raised: $4.7M. Latest round: Grant. Key investors include Flyover Capital, Alpaca, Atria Ventures, Blu Ventures, Looking Glass Capital, Redbud VC, The Council, Gaingels.
- Founded
- 2023
- Headquarters
- Kansas City, Missouri, United States
- Team size
- 1-10
- Total funding
- $4.7M
Value proposition
To accelerate clinical trial enrollment and drug development by accurately and efficiently matching patients with clinical trials, thereby reducing costs and time.
Products and solutions
Trially Match: HIPAA-compliant LLM-powered patient matching and prescreening using structured and unstructured clinical data., Trially Connect / Margo: Agentic patient outreach, prescreening, scheduling and follow-up; English/Spanish language capability announced in July 2026., Trially Intelligence: Pipeline radar and patient-population feasibility analytics to identify suitable trials.
Unique value
Trially is the first AI-native platform for clinical trial enrollment that uses HIPAA-compliant LLM agents to analyze unstructured medical data, a process that is typically manual and time-consuming.
Target customer
Sponsors of clinical trials, Contract Research Organizations (CROs), and clinical trial sites/healthcare providers.
Industries served
Healthcare, Pharmaceuticals, Life Sciences
Technology advantage
The use of proprietary AI and LLM agents provides a significant speed and efficiency advantage over traditional manual methods, leading to faster enrollment, higher accuracy (2-6x increase in enrollment rate, 73% fewer screen fails), and lower costs.
How they differentiate
Trially differentiates itself by using an AI-native platform with HIPAA-compliant LLM agents to analyze unstructured medical data. This allows for faster and more accurate matching of patients to clinical trials, transforming a traditionally manual and time-consuming process into a more efficient one.
Main competitors
Deep 6 AI, Medidata, Verily
Key partnerships
athenahealth (Marketplace Partner), ClinTrial Research (CTR) (Strategic Partnership)
Notable customers
ClinTrial Research (CTR), Helios Clinical Research
Major milestones
Secured $4.7M in Seed Funding., Launched 'Margo', an AI solution for patient matching., Joined athenahealth's Marketplace to extend its reach to a large network of healthcare providers.
Growth metrics
Specific growth metrics are not publicly available. However, the company claims a 2-6x increase in enrollment rate, 73% fewer screen fails, and 91% less prescreening time for its customers.
Market positioning
Trially is positioned as an AI-first clinical trial recruitment platform that aims to accelerate the delivery of new therapies by solving the patient recruitment bottleneck. They target sponsors, CROs, and research sites, offering a solution to increase enrollment rates and reduce screen fails.
Geographic focus
United States
Patents and IP
Information not publicly available.
About Kyle McAllister
Experienced Co-Founder with a demonstrated history of working in the hospital & health care industry. Skilled in HIPAA, SaaS, Healthcare IT (HIT), and Business Development.
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Official website: https://www.trially.ai